domingo, 15 de abril de 2018

Childhood Soft Tissue Sarcoma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

Childhood Soft Tissue Sarcoma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

National Cancer Institute

Childhood Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version

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Changes to This Summary (04/02/2018)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Added text to state that a small series reported symptomatic improvement and stable disease in seven patients with desmoid-type fibromatosis who were treated with pazopanib (cited Agresta et al. as reference 48).
Added text to state that a tumor with morphology similar to that of infantile fibrosarcoma has been identified in older children; in these older children, the tumors do not have the t(12;15)(ETV-NTRK3) translocation that is characteristic of the younger patients. In several of these patients, BRAF gene fusions have been identified (cited Kao et al. as reference 69).
Added text about the outcome results of 73 children and adolescents with recurrent malignant peripheral nerve sheath tumor reported by the Italian Sarcoma Group (cited Bergamaschi et al. as reference 127 and level of evidence 3iiiA).
Added text about the patient characteristics and results of a retrospective review of children and young adults younger than 30 years from four institutions, which identified 69 patients with alveolar soft part sarcoma treated primarily with surgery between 1980 and 2014 (cited Flores et al. as reference 152 and level of evidence 3iiA).
Added Sedig et al. as reference 172 and level of evidence 3iiiA.
Added text about the prognostic factors and outcome results reported in an Italian review of 73 children and adolescents with recurrent malignant peripheral nerve sheath tumor (cited Bergamaschi et al. as reference 1 and level of evidence 3iiiA).
This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.
  • Updated: April 2, 2018

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