Childhood Rhabdomyosarcoma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

Childhood Rhabdomyosarcoma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

Childhood Rhabdomyosarcoma Treatment (PDQ®)–Health Professional Version

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SOFT TISSUE SARCOMA

• Patient
• Health Professional
  • Adult Soft Tissue Sarcoma Treatment
  • GI Stromal Tumors Treatment
  • Kaposi Sarcoma Treatment
  • Childhood Rhabdomyosarcoma Treatment
  • Childhood Soft Tissue Sarcoma Treatment
  • Childhood Vascular Tumors Treatment
• Research

SECTIONS

• General Information About Childhood Rhabdomyosarcoma
• Cellular Classification for Childhood Rhabdomyosarcoma
• Stage Information for Childhood Rhabdomyosarcoma
• Treatment Option Overview for Childhood Rhabdomyosarcoma
• Treatment of Previously Untreated Childhood Rhabdomyosarcoma
• Treatment of Refractory or Recurrent Childhood Rhabdomyosarcoma
• Changes to This Summary (04/​04/​2018)
• About This PDQ Summary
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Changes to This Summary (04/04/2018)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information About Childhood Rhabdomyosarcoma

Revised text to state that it is unlikely that response to induction chemotherapy, as judged by anatomic imaging, correlates with the likelihood of survival in patients with rhabdomyosarcoma, on the basis of the Intergroup Rhabdomyosarcoma Study Group, Children's Oncology Group, and International Society of Pediatric Oncology studies that found no association (cited Vaarwerk et al. as reference 63 and level of evidence 3iiiA).

Treatment of Previously Untreated Childhood Rhabdomyosarcoma

Added text about the results of a study on the patterns of failure in 11 of 66 children with nonmetastatic rhabdomyosarcoma who were treated with proton radiation therapy (cited Vern-Gross et al. as reference 25).

Added Affinita et al. as reference 60 and level of evidence 3iiA.

Added text about a single-institution study of 28 patients aged 6 months to 32 years with soft tissue sarcomas that prospectively compared sentinel lymph node biopsy with positron emission tomography–computed tomography scan for the detection of lymph node metastases (cited Wagner et al. as reference 81).

Added Fuchs et al. as reference 117.

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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About This PDQ Summary

• Updated: April 4, 2018