herenciageneticayenfermedad: Genetics

jueves, 9 de noviembre de 2017

Genetics - Nov 8, 2017 Edition

	November 8, 2017
	Genetics
	The latest Genetics news from News Medical

	Discovery of genetic markers could guide individualized treatments for advanced prostate cancer Researchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced prostate cancer.

	An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

	Study provides rare glimpse into genetic transmission of herpes simplex virus from father to son A new study explores how herpes simplex virus might change when passed from one individual to another, information that may prove useful in future development of therapeutics and vaccines.

			SBP researchers identify new protective function for brain protein genetically linked to Alzheimer's Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a new protective function for a brain protein genetically linked to Alzheimer's. The findings, published in the Journal of Experimental Medicine, could inform novel treatment strategies.

			Genetic Regulation of Fingers and Toes Development Generally, the limb buds of an embryo develop at the first trimester of pregnancy, which is followed by the growth of fingers and toes. Limb patterning usually refers to the shaping of hands and feet, which directly involve the fingers and toes respectively.

			Scientists identify eight new genes involved in epileptic encephalopathy Approximately 30 per cent of patients with epilepsy do not respond to anti-epileptic drugs. In these cases, all neurologists can do is attempt to find the right combination of medication through trial and error.

	Research provides path to possible treatment for Fragile X Syndrome and other types of autism In Fragile X Syndrome--the leading genetic form of intellectual disability and autism--the effects of a single defective gene ripple through a series of chemical pathways, altering signals between brain cells.

	Roundworms may provide new clues to nicotine dependence Researchers at the University of Michigan Life Sciences Institute found that a previously dismissed genetic mechanism may contribute to nicotine dependence, and to the withdrawal effects that can make quitting smoking so difficult.

	WISDOM trial aims to identify best way to screen for breast cancer Since her 40s, Lilly Lidot has received yearly mammograms. Her sister did not get regular checkups, so when her cancer was diagnosed it had already spread to her brain. Lilly's sister died in 2010.

	Researchers show how changes along lining of mammary ducts can lead to breast cancer Breast cancer researchers have mapped early genetic alterations in normal-looking cells at various distances from primary tumors to show how changes along the lining of mammary ducts can lead to disease.

	Researchers compile biggest recorded collection of families with epilepsy Researchers from Swansea University Medical School have joined up with five other centers from around the world to compile the biggest recorded collection of families with forms of epilepsy where genetics may play a part in the recurring feature of the condition.

	Study solves critical piece of deafness puzzle by identifying long non-coding RNAs A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system.

	Molecular tests to detect Zika virus should be repeated more than once in pregnant women Molecular tests to detect Zika virus, which enable identification of the pathogen's genetic material in body fluids, such as blood, urine, semen and saliva during the acute phase of infection, have been used routinely in prenatal checkups for pregnant women with symptoms of the disease.

	Malnutrition problems may be traced to diets divergent from food in evolutionary past Malnutrition problems can be traced to poor-quality diets lacking in diversity, a recent phenomenon in evolutionary history, according to a new paper from the Brown School at Washington University in St. Louis.

	Drug can safely and effectively help infants with SMA gain muscle function, study shows More than half of the babies with infantile-onset spinal muscular atrophy (SMA) who were treated with nusinersen (Spinraza) gained motor milestones, compared to none of the babies in the control group. Infants treated with the drug also had 63 percent lower risk of death.

	FDA approves first targeted cancer treatment based on basket study The US Food and Drug Administration has announced that it has approved the drug vemurafenib for the treatment of patients with BRAF V600-mutant Erdheim-Chester disease (ECD).

	Scientists one step closer to solving puzzle of how nerves can self-heal Monash University scientists are one step closer to solving the riddle of how nerves can self-heal. The scientists from the Biomedicine Discovery Institute (BDI) have found signals in the tiny transparent roundworm that control the mechanism by which severed nerves self-heal.

	Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease Stem cells taken from muscle tissue could promote better blood flow in patients with diabetes who develop peripheral artery disease, a painful complication that can require surgery or lead to amputation.

	FDA approves new drug Zelboraf for Erdheim-Chester disease The United States Food and Drugs Administration (FDA) has approved Zelboraf (vemurafenib), a drug for the treatment of adults with a are type of blood cancer called Erdheim-Chester Disease or ECD.

	Review explains nuances of non-invasive prenatal screening for pregnant women As the use of non-invasive prenatal screening (NIPS) grows, there has been concern within the medical community that a poor understanding of this technique among clinicians and patients could negatively impact pregnancies.