The Microbiome & Innovations to Slow Antibiotic Resistance
Applied Microbiome Research to Improve Public Health
- How Antibiotics Disrupt a Healthy Microbiome – CDC and investigators will study novel strategies that can protect and restore the microbiome, and determine how exposure to antibiotics early in life affects microbiome development.
- How a Disrupted Microbiome Puts People at Risk – CDC and investigators will develop a predictive index that identifies a patient’s risk of disruption from a specific antibiotic, to carry antibiotic-resistant bacteria, or become infected with one. CDC and investigators will also work to develop and test microbiome measurements that monitor a patient’s risk for disruption, and assess enhanced infection control triggers.
- How Antibiotic Stewardship Can Protect the Microbiome – CDC and investigators will improve strategies to tailor antibiotic stewardship to a patient’s individual microbiome, as well as assess how to fit antibiotic stewardship to a specific population of patients (e.g., hospital unit, nursing home, doctor’s office).
Innovations to Track & Prevent Antibiotic-Resistant Infections
Antibiotic Resistance (AR) Solutions Initiative: Microbiome
CDC’s AR Solutions Initiative will measure the impact of antibiotics on the human microbiome to better understand the relationships among antibiotics, antibiotic resistance, and human health
- A healthy microbiome helps protect you from infection. Improved antibiotic use and a healthy microbiome can keep us and our communities well.
- Antibiotics disrupt your microbiome, wiping out both good and bad bacteria.
- Tough-to-kill bacteria—like MRSA, CRE, and C. difficile—can take advantage of this disruption and multiply.
- With this overgrowth of resistant bacteria, your body is primed for infection. Once colonized, you can easily spread the resistant bacteria with others.
- How do antibiotics disrupt a healthy microbiome?
- How does a disrupted microbiome put us at risk?
- How can tailoring antibiotic use protect the microbiome?