domingo, 8 de noviembre de 2015

ACTUALIZACIÓN MÉDICO-CONTINUADA EN ENFERMEDADES EPIDEMIOLÓGICAMENTE "COMUNICABLES" ► NUEVO CAPÍTULO MÉDICO ► Advanced Molecular Detection Clips Content || Public Health Genomics Knowledge Base (beta version)

Public Health Genomics Knowledge Base (beta version)

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Advanced Molecular Detection Clips

los capítulos incluidos en esta sección, se actualizarán semanalmente, incorporando documentos y accesos a nuevas bases de datos que actualmente están en desarrollo... los contenidos, como es costumbre en secciones avanzadas, están únicamente en idioma inglés y reflejan los últimos contenidos editados en cada materia en todo el mundo...



Spotlight

Host Genetic Susceptibility to Enteric Viruses: A Systematic Review and Metaanalysis.Norovirus and rotavirus are prominent enteric viruses responsible for severe acute gastroenteritis disease burden around the world. Both viruses recognize and bind to histo-blood group antigens, which are expressed by the fucosyltransferase 2 (FUT2) gene. Individuals with a functional FUT2 gene are termed "secretors." FUT2 polymorphisms may influence viral binding patterns and, therefore, may influence host susceptibility to infection by these viruses.... Our analyses indicate that host genetic susceptibility to norovirus and rotavirus infection may be strain specific. As strain distribution and the proportion of genetic phenotypes vary in different countries, future studies should focus on differences in susceptibility among various ethnicities. Knowledge of innate susceptibility to rotavirus and norovirus can lead to improved understanding of both vaccine performance and individual risk of disease.

About Advanced Molecular Detection Clips

Advanced Molecular Detection(AMD) Clips are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. Special emphasis is given to the use of next-generation genetic sequencing in public health surveillance, investigation, and development of new diagnostics and interventions. The collection is not comprehensive but aims to capture highlights, while surveying a wide range of topics. CDC-authored articles are flagged.





EVENTS / TRAINING / WEB RESOURCES


POLICY


CONCEPTS / COMMENTS


METHODS / TOOLS


EVOLUTION / ECOLOGY / POPULATIONS


PATHOGENICITY / ANTIMICROBIAL RESISTANCE


DETECTION / DIAGNOSIS


EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION


HOST-MICROBE INTERACTIONS

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