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Genomics|Features|Mosquito-borne Disease

Mosquito-borne Disease

Mosquito-borne Disease: Public Health and Genomic Insights - August 31, 2015

CDC Info

• Prevent mosquito bites
• Chikungunya virus
• Notes from the field: Chikungunya virus spreads in the Americas — Caribbean and South America, 2013–2014MMWR 2014. 63(22);500-501.

Replacing pesticides with genetics, by D Powell, New York Times, August 31, 2015

CDC information:Prevent mosquito bites

Suppression of a field population of Aedes aegypti in Brazil by sustained release of transgenic male mosquitoes.
Carvalho DO et al. PLoS Negl Trop Dis 2015 Jul (7) e0003864

Can genetically modified mosquitoes curb Dengue fever? PBS Newshour, May 16

Buzzkill: regulatory uncertainty plagues rollout of genetically modified mosquitoes
Chakradhar S , Nature Medicine, May 7, 2015

Awareness and support of release of genetically modified "sterile" mosquitoes, Key West, Florida, USA.
Ernst KC et al. Emerging Infect. Dis. 2015 Feb (2) 320-4

Silencing the buzz: a new approach to population suppression of mosquitoes by feeding larvae double-stranded RNAs.
Whyard S et al. Parasit Vectors 2015 96

Chikungunya: Recent Genomics and Public Health Insights - May 15, 2015

Dengue and Chikungunya in our backyard: Preventing Aedes mosquito-borne disease, CDC Public Health Grand Rounds, May 2015

The burden of Dengue and Chikungunya worldwide: Implications for the Southern United States and California.
Fredericks AC et al. Ann Glob Health 2014 Nov-Dec (6) 466-475

Therapeutics and vaccines against chikungunya virus.
Ahola T et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 250-7

Updates on chikungunya epidemiology, clinical disease, and diagnostics.
Sam I-Ching et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 223-30

Chikungunya virus and the global spread of a mosquito-borne disease.
Weaver SC et al. N. Engl. J. Med. 2015 Mar 26. (13) 1231-9

High throughput proteomic analysis and a comparative review identify the nuclear chaperone, Nucleophosmin among the common set of proteins modulated in Chikungunya virus infection.
Abraham R et al. J Proteomics 2015 Apr 29. 126-41

New approaches to chikungunya virus vaccine development.
Garcia A et al. Recent Pat Inflamm Allergy Drug Discov 2015 (1) 31-7

Chikungunya virus and its mosquito vectors.
Higgs S et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 231-40

Chikungunya: Establishing a new home in the western hemisphere.
Davidson H. Hamer et al. Annals of Internal Medicine, December 2014

While Americans watched for Ebola in 2014, another painful virus slipped into the U.S. and it's just getting started, NPR News, Jan 1, 2015

Next generation sequencing reveals regulation of distinct Aedes microRNAs during chikungunya virus development. 
Shrinet J, et al. PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2616

Comprehensive proteomic analysis of white blood cells from chikungunya fever patients of different severities. 
Wikan N, et al. J Transl Med. 2014 Apr 11;12:96.

Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection 
Poo YS, et al. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3354

Dengue: Public Health and Genomic Insights - May 15, 2015

Dengue and Chikungunya in our backyard: Preventing aedes mosquito-borne disease, CDC Public Health Grand Rounds, May 2015

CDC information: Dengue virus is a leading cause of illness and death in the tropics and subtropics.

Check out genes reported in relation to Dengue occurrence and outcomes, from the HuGE Navigator

The burden of Dengue and Chikungunya worldwide: Implications for the Southern United States and California.
Fredericks AC et al. Ann Glob Health 2014 Nov-Dec (6) 466-475

A critical assessment of vector control for Dengue prevention.
Achee NL et al. PLoS Negl Trop Dis 2015 May (5) e0003655

Reviewing Dengue: Still a neglected tropical disease?
Horstick O et al. PLoS Negl Trop Dis 2015 Apr (4) e0003632

Dengue pathogenesis: a disease driven by the host response.
Martina BE et al. Sci Prog 2014 (Pt 3) 197-214

Review: progress in the diagnosis of dengue virus infections and importance of point of care test: a review.
Fatima A et al. Pak J Pharm Sci 2015 Jan (1) 271-80

Targeting host factors to treat West Nile and dengue viral infections.
Krishnan MN et al. Viruses 2014 Feb (2) 683-708

A combined genetic-proteomic approach identifies residues within Dengue virus NS4B critical for interaction with NS3 and viral replication.
Chatel-Chaix L et al. J. Virol. 2015 Apr 29.

Molecular epidemiology of Dengue viruses co-circulating in upper Myanmar in 2006.
Thant KZ et al. Trop Med Health 2015 Mar (1) 21-7

Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti.
Kistler KE et al. Cell Rep 2015 Apr 7. (1) 51-60

Clinical outcome and genetic differences within a monophyletic Dengue virus type 2 population.
Hapuarachchi HC et al. PLoS ONE 2015 (3) e0121696

Genomic analysis and growth characteristic of dengue viruses from Makassar, Indonesia.
Sasmono RT et al. Infect. Genet. Evol. 2015 Jun 165-77

A multipurpose, high-throughput single-nucleotide polymorphism chip for the Dengue and Yellow Fever mosquito, Aedes aegypti.
Evans BR et al. G3 (Bethesda) 2015 (5) 711-8

Complete genome sequencing and phylogenetic analysis of dengue type 1 virus isolated from Jeddah, Saudi Arabia.
Azhar EI et al. Virol. J. 2015 (1) 1