Obesity
Obesity: Public Health and Genomic Insights - May 12, 2015
CDC and Related Info
- CDC information on obesity
- New CDC state obesity map now available
- Genes reported in relation to obesity, including genomewide association studies via theHuGE Navigator
What is obesity? Metabolic signatures offer new comprehensive view,
Francis Collins, NIH Director Blog, May 12, 2015
Francis Collins, NIH Director Blog, May 12, 2015Genomic knowledge is power in the fight against obesity, by Bruce Agnew, NHGRI, May 2015
by Bruce Agnew, NHGRI, May 2015Transgenerational inheritance of metabolic disease.
Stegemann R et al. Semin. Cell Dev. Biol. 2015 Apr 29.
Stegemann R et al. Semin. Cell Dev. Biol. 2015 Apr 29.
Epigenome-wide association study (EWAS) of BMI, BMI change, and waist circumference in African American adults identifies multiple replicated loci.
Demerath EW et al. Hum. Mol. Genet. 2015 May 1.
Demerath EW et al. Hum. Mol. Genet. 2015 May 1.
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.
Bonhoure N et al. Genes Dev. 2015 May 1. (9) 934-47
Bonhoure N et al. Genes Dev. 2015 May 1. (9) 934-47
The role of the gut microbiota in metabolic health.
Janssen AW et al. FASEB J. 2015 Apr 28.
Janssen AW et al. FASEB J. 2015 Apr 28.
Interactions between obesity-related copy number variants and dietary behaviors in childhood obesity.
Zhang D et al. Nutrients 2015 (4) 3054-66
Zhang D et al. Nutrients 2015 (4) 3054-66
The metabolome profiling and pathway analysis in metabolic healthy and abnormal obesity.
Chen H-H et al. Int J Obes (Lond) 2015 Apr 24.
Chen H-H et al. Int J Obes (Lond) 2015 Apr 24.
Mothers' guilt responses to children's obesity risk feedback.
Persky S et al. J Health Psychol 2015 May (5) 649-58
Persky S et al. J Health Psychol 2015 May (5) 649-58
A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder.
Hung Chi-Fa et al. BMC Med 2015 86
Hung Chi-Fa et al. BMC Med 2015 86
Genome-wide screen of DNA methylation identifies novel markers in childhood obesity.
Ding Xu et al. Gene 2015 Apr 12.
Ding Xu et al. Gene 2015 Apr 12.
Obesity: interactions of genome and nutrients intake.
Doo Miae et al. Prev Nutr Food Sci 2015 Mar (1) 1-7
Doo Miae et al. Prev Nutr Food Sci 2015 Mar (1) 1-7
Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.
Ollikainen M et al. Clin Epigenetics 2015 (1) 39
Ollikainen M et al. Clin Epigenetics 2015 (1) 39
Genome-wide expression in visceral adipose tissue from obese prepubertal children.
Aguilera CM et al. Int J Mol Sci 2015 (4) 7723-37
Aguilera CM et al. Int J Mol Sci 2015 (4) 7723-37
Obesity: New Genomic Insights - March 30, 2015
The Hunger Genes: Pathways to obesity
van der Klaauw AA et al. Cell, March 26, 2015
van der Klaauw AA et al. Cell, March 26, 2015
Polymorphisms in endothelin system genes, arsenic levels and obesity risk.
Martínez-Barquero V et al. PLoS ONE 2015 (3) e0118471
Martínez-Barquero V et al. PLoS ONE 2015 (3) e0118471
Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals.
Nead KT et al. Hum. Mol. Genet. 2015 Mar 17.
Nead KT et al. Hum. Mol. Genet. 2015 Mar 17.
Gene-environment interactions and obesity: recent developments and future directions.
Huang T et al. BMC Med Genomics 2015 530
Huang T et al. BMC Med Genomics 2015 530
Genetic studies yield new insights into obesity by Dr. Francis Collins, NIH Director's Blog, Feb 19
by Dr. Francis Collins, NIH Director's Blog, Feb 19Weighty impact of new genetic fat map , by Rebecca Burbridge, PHG Foundation, Feb 13
by Rebecca Burbridge, PHG Foundation, Feb 13Genetic studies of body mass index yield new insights for obesity biology.
Locke Adam E et al. Nature 2015 Feb 12. (7538) 197-206
Locke Adam E et al. Nature 2015 Feb 12. (7538) 197-206
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin Dmitry et al. Nature 2015 Feb 12. (7538) 187-96
Shungin Dmitry et al. Nature 2015 Feb 12. (7538) 187-96
Lipid exposure elicits differential responses in gene expression and DNA methylation in primary human skeletal muscle cells from severely obese women.
Maples Jill M et al. Physiol. Genomics 2015 Feb 10.
Maples Jill M et al. Physiol. Genomics 2015 Feb 10.
Associations between TRPV4 genotypes and body mass index in Taiwanese subjects.
Duan De-Min et al. Mol. Genet. Genomics 2015 Feb 3.
Duan De-Min et al. Mol. Genet. Genomics 2015 Feb 3.
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Wessel Jennifer et al. Nat Commun 2015 5897
Wessel Jennifer et al. Nat Commun 2015 5897
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
Mahajan Anubha et al. PLoS Genet. 2015 Jan (1) e1004876
Mahajan Anubha et al. PLoS Genet. 2015 Jan (1) e1004876
Obesity breakthrough: Researchers identify new genetic markers for obesity in largest-ever genomic study on the disease, International Business Times, Feb 11
International Business Times, Feb 11Obesity: Recent Public Health and Genomic Insights- January 8, 2015
Life years lost and lifetime healthcare expenditures associated with diabetes in the U.S., National Health Interview Survey, 1997-2000.
Leung MM, et al. Diabetes Care. 2014 Dec 31.
Cohort of birth modifies the association between FTO genotype and BMI.
James Niels Rosenquist, et al. PNAS, December 2014
Leung MM, et al. Diabetes Care. 2014 Dec 31.
Cohort of birth modifies the association between FTO genotype and BMI.
James Niels Rosenquist, et al. PNAS, December 2014
Gene linked to obesity hasn’t always been a problem, study finds, New York Times, Dec 31, 2014
New York Times, Dec 31, 2014FTO and obesity: mechanisms of association.
Zhao X, et al. Curr Diab Rep. 2014;14(5):486
Zhao X, et al. Curr Diab Rep. 2014;14(5):486
Nutritional genomics and metabolomics in obesity and type 2 diabetes.
Frank B Hu et al. BMC Genomics 2014, 15(Suppl 2):O10
Frank B Hu et al. BMC Genomics 2014, 15(Suppl 2):O10
Advances in exercise, fitness, and performance genomics in 2013.
Wolfarth B, et al. Med Sci Sports Exerc. 2014;46(5):851-9
Wolfarth B, et al. Med Sci Sports Exerc. 2014;46(5):851-9
Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies.
Basile KJ, et al. Int J Endocrinol. 2014;2014:769671
Basile KJ, et al. Int J Endocrinol. 2014;2014:769671
Obesity: Genes, Environment & Public Health - September 11, 2014
CDC media advisory: New CDC state obesity map now available, Sep 4
CDC information: Obesity prevalence in 2013 varies across states and regions
CDC information: Genomics and health- Behavior, environment, and genetic factors all have a role in causing people to be overweight and obese
Did you know? More than 1660 genes have been reported in relation to obesity occurrence and outcomes including 178 genomewide association studies? To find out more, visit the HuGE Navigator
Genes are not destiny. Obesity-promoting genes in an obesity-promoting world, Harvard School of Public Health
Harvard School of Public Health It's not all in the genes, Tim Caulfield, Policy Options, Jul 2014
Tim Caulfield, Policy Options, Jul 2014The application of public health genomics to the prevention and management of obesity in the UK, PHG Foundation (2013)
PHG Foundation (2013)Ancient famine-fighting genes can't explain obesity. Scientists look beyond calorie-hoarding genes to understand widening waistlines, by Laura Beil, Science News, Sep 5
by Laura Beil, Science News, Sep 5
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