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Genomics|Features|Malaria

Malaria

Malaria: Resistance: Role of Genomics - December 30, 2014

The genetics of resistant malaria. 
Gretchen Vogel et al. Science, December 11, 2014

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.
Rout S, et al.  J Microbiol Methods. 2014 Dec 5

Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers.
Almelli T, et al. PLoS One. 2014 Dec 5;9(12):e114401

Drug resistance genomics of the antimalarial drug artemisinin.
Winzeler EA, Manary MJ. Genome Biol. 2014 Nov 25

Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism haplotypes of IFN-α receptor (IFNAR1) associated with enhanced malaria susceptibility in Indian populations.
Kanchan K, et al. Infect Genet Evol. 2014 Nov 7;

Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes.
Ingham VA, et al. BMC Genomics. 2014 Nov 25;

Malaria: Recent Genomic Insights - September 11, 2014

CDC information: More than 200 million cases of malaria occur worldwide every year

CDC information: Replacing outdated malaria drug resistance screening methods with next-generation molecular tools and techniques

CDC information: Protective effects of sickle cell trait against malaria-associated mortality and morbidity

Malaria diagnostics and surveillance in the post-genomic era: A review 
Lucchi N, Oberstaller L, Kissinger J, et al. Public Health Genomics, 2013;16:37-43

Did you know? 230 genes have been reported in relation to risk or outcomes of malaria, including 8 genomewide association studies. Find out more using the HuGE Navigator

A genomic revolution in malaria research, by Olivo Miotto, Wellcome Trust Sanger Institute blog post, Jan 10, 2014

Resistance gene identified in malaria parasite, by Ewen Callaway, Nature News, Dec 18, 2013

Genomics reveals mechanism for malaria drug resistance, Drug Discovery & Development, Jul 25, 2014

Single-cell genomics for dissection of complex malaria infections. 
Shalini Nair et al. Genome Research, May 2014

Recent CDC paper: Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda
Mbogo GW, et al.  Am J Trop Med Hyg. 2014 May 5.  

Preferential feeding success of laboratory reared Anopheles stephensi mosquitoes according to ABO blood group status. 
Anjomruz M  et al. Acta Trop. 2014 Aug 20.